You can probably figure it out from the title, but it's about people who can't let go of things; their houses are literally packed with random stuff with no rhyme or reason to what or why something is there. The show also features clinical psychologists who come in and talk to the hoarders to determine the cause for their hoarding behavior. These psychologists are extremely important because often (if not every time) this hoarding stems from some psychological hang-up.
I imagine that many people watching this show are looking at the hoarders with judgement in their eyes; in disbelief that someone could let their homes, in some cases their lives, deteriorate to such a point. I take a different approach.
I think these hoarders are better off than many. If you walk into their homes, their attachment is apparent; a clear marker pointing to some other deep seated issue. Many of us, aren't nearly so lucky. Our hangups, our attachments only become apparent under specific conditions i.e. when we're criticized, in a relationship. These situation based attachments are easily ignored because they don't plague us everyday, but their influence is no less powerful; both preventing us from being more balanced and living the way we are capable of living.
I'm not saying that everyone has an unhealthy attachment, but if you did, how would you know? What would your markers be? Are you self-reflective enough to honestly ask yourself, "What's in my hoard?"